Loss of the maternal H19 gene induces changes in Igf2 methylation in both cis and trans

Recent investigations have shown that the maintenance of genomic imprinting of the murine insulin-like growth factor 2 (Igf2) gene involves at least two factors: the DNA (cytosine-5-)-methyltransferase activity, which is required to preserve the paternal specific expression of Igf2, and the H19 gene...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Forné, T., Oswald, J., Dean, W., Saam, J. R., Bailleul, B., Dandolo, L., Tilghman, S. M., Walter, J., Reik, W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23347/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9294195/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.19.10243
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