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The α chain of laminin-1 is independently secreted and drives secretion of its β- and γ-chain partners

A mammalian recombinant strategy was established to dissect rules of basement membrane laminin assembly and secretion. The α-, β-, and γ-chain subunits of laminin-1 were expressed in all combinations, transiently and/or stably, in a near-null background. In the absence of its normal partners, the α...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Yurchenco, Peter D., Quan, Yong, Colognato, Holly, Mathus, Todd, Harrison, David, Yamada, Yoshihiko, O’Rear, Julian J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23337/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9294185/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.19.10189
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