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Selection for citrate synthase deficiency in icd mutants of Escherichia coli.

Cultures of isocitrate dehydrogenase-deficient (icd) mutants were overgrown by double mutants (icd glt) lacking citrate synthase activity also. The icd mutants grew more slowly than wild-type cells or the double mutants because they accumulated an inhibitory metabolite (possibly citrate). Intracellu...

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Autori principali: Lakshmi, T M, Helling, R B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1976
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC233035/
https://ncbi.nlm.nih.gov/pubmed/776950
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