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Construction of a Functional CMP-Sialic Acid Biosynthesis Pathway in Arabidopsis

Previous studies have reported that plants contain negligible amounts of free or protein-bound N-acetylneuraminic acid (Neu5Ac). This is a major disadvantage for the use of plants as a biopharmaceutical expression system, since N-glycans with terminal Neu5Ac residues are important for the biological...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Castilho, Alexandra, Pabst, Martin, Leonard, Renaud, Veit, Christiane, Altmann, Friedrich, Mach, Lukas, Glössl, Josef, Strasser, Richard, Steinkellner, Herta
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Plant Biologists 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330290/
https://ncbi.nlm.nih.gov/pubmed/18326787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.108.117572
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