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TIM-4 structures identify a Metal Ion-dependent Ligand Binding Site where phosphatidylserine binds
The T-cell immunoglobulin and mucin domain (TIM) proteins are important regulators of T cell responses. They have been linked to autoimmunity and cancer. Structures of the murine TIM-4 identified a Metal Ion-dependent Ligand Binding Site (MILIBS) in the immunoglobulin (Ig) domain of the TIM family....
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2330274/ https://ncbi.nlm.nih.gov/pubmed/18083575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.11.008 |
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