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The activation domain of the enhancer binding protein p45NF-E2 interacts with TAF(II)130 and mediates long-range activation of the α- and β-globin gene loci in an erythroid cell line

We have used the interaction between the erythroid-specific enhancer in hypersensitivity site 2 of the human β-globin locus control region and the globin gene promoters as a paradigm to examine the mechanisms governing promoter/enhancer interactions in this locus. We have demonstrated that enhancer-...

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Autors principals: Amrolia, Persis J., Ramamurthy, Lakshman, Saluja, Daman, Tanese, Naoko, Jane, Stephen M., Cunningham, John M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23301/
https://ncbi.nlm.nih.gov/pubmed/9294161
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