Transient T cell depletion causes regression of melanoma metastases

BACKGROUND: Cognate immunity against neoplastic cells depends on a balance between effector T cells and regulatory T (Treg) cells. Treg cells prevent immune attack against normal and neoplastic cells by directly suppressing the activation of effector CD4(+ )and CD8(+ )T cells. We postulated that a r...

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Main Authors: Rasku, Mary Ann, Clem, Amy L, Telang, Sucheta, Taft, Beverly, Gettings, Kelly, Gragg, Hana, Cramer, Daniel, Lear, Sheron C, McMasters, Kelly M, Miller, Donald M, Chesney, Jason
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330026/
https://ncbi.nlm.nih.gov/pubmed/18334033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-6-12
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