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Structural characterization of the Yersinia pestis type III secretion system needle protein YscF in complex with its heterodimeric chaperone YscE/YscG

The plague-causing bacterium Yersinia pestis utilizes a Type III Secretion System (T3SS) to deliver effector proteins into mammalian cells where they interfere with signal transduction pathways that mediate phagocytosis and the inflammatory response. Effector proteins are injected through a hollow n...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sun, Ping, Tropea, Joseph E., Austin, Brian P., Cherry, Scott, Waugh, David S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329918/
https://ncbi.nlm.nih.gov/pubmed/18281060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.12.067
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