Tissue Inhibitor of Metalloproteinase-1 Moderates Airway Re-Epithelialization by Regulating Matrilysin Activity

Obliterative bronchiolitis (OB) is the histopathological finding in chronic lung allograft rejection. Mounting evidence suggests that epithelial damage drives the development of airway fibrosis in OB. Tissue inhibitor of metalloproteinase (TIMP)-1 expression increases in lung allografts and is assoc...

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Autori principali: Chen, Peter, McGuire, John K., Hackman, Robert C., Kim, Kyoung-Hee, Black, Roy A., Poindexter, Kurt, Yan, Wei, Liu, Phillip, Chen, Ann J., Parks, William C., Madtes, David K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2008
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329835/
https://ncbi.nlm.nih.gov/pubmed/18385523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070891
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