Presence of HIF-1 and related genes in normal mucosa, adenomas and carcinomas of the colorectum

Expression of the transcription factor hypoxia-inducible factor 1 (HIF-1), which plays a key role in cellular adaptation to hypoxia, was investigated in normal colorectal mucosa (ten), adenomas (61), and carcinomas (23). Tissue samples were analyzed for HIF-1α, its upstream regulators, von Hippel–Li...

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Autori principali: Greijer, Astrid E., Delis-van Diemen, Pien M., Fijneman, Remond J. A., Giles, Rachel H., Voest, Emile E., van Hinsbergh, Victor W. M., Meijer, Gerrit A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2008
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329727/
https://ncbi.nlm.nih.gov/pubmed/18351386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00428-008-0578-9
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