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Identification and evolution of fungal mitochondrial tyrosyl-tRNA synthetases with group I intron splicing activity

The bifunctional Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18 protein) both aminoacylates mitochondrial tRNA(Tyr) and acts as a structure-stabilizing splicing cofactor for group I introns. Previous studies showed that CYT-18 has distinct tRNA(Tyr) and group I intron-binding sites,...

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Main Authors: Paukstelis, Paul J., Lambowitz, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329719/
https://ncbi.nlm.nih.gov/pubmed/18413600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801722105
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