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Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus

Bacillus anthracis, the etiologic agent of anthrax, avoids immune surveillance and commandeers host macrophages as a vehicle for lymphatic spreading. Here, we show that B. anthracis edema toxin (ET), via its adenylyl cyclase activity, dramatically increases the motility of infected macrophages and t...

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Detalhes bibliográficos
Main Authors: Kim, Chun, Wilcox-Adelman, Sarah, Sano, Yasuyo, Tang, Wei-Jen, Collier, R. John, Park, Jin Mo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329691/
https://ncbi.nlm.nih.gov/pubmed/18427110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800105105
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