R-spondin1 and FOXL2 act into two distinct cellular types during goat ovarian differentiation

BACKGROUND: Up to now, two loci have been involved in XX sex-reversal in mammals following loss-of-function mutations, PIS (Polled Intersex Syndrome) in goats and R-spondin1 (RSPO1) in humans. Here, we analyze the possible interaction between these two factors during goat gonad development. Furtherm...

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Hlavní autoři: Kocer, Ayhan, Pinheiro, Iris, Pannetier, Maëlle, Renault, Lauriane, Parma, Pietro, Radi, Orietta, Kim, Kyung-Ah, Camerino, Giovanna, Pailhoux, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329615/
https://ncbi.nlm.nih.gov/pubmed/18384673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-8-36
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