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Absence of Gonadotropin-Releasing Hormone 1 and Kiss1 Activation in α-Fetoprotein Knockout Mice: Prenatal Estrogens Defeminize the Potential to Show Preovulatory Luteinizing Hormone Surges

Sex differences in gonadal function are driven by either cyclical (females) or tonic (males) hypothalamic GnRH1 release and, subsequently, gonadotrophin (LH and FSH) secretion from the pituitary. This sex difference seems to depend on the perinatal actions of gonadal hormones on the hypothalamus. We...

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Detalhes bibliográficos
Main Authors: González-Martínez, David, De Mees, Christelle, Douhard, Quentin, Szpirer, Claude, Bakker, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329285/
https://ncbi.nlm.nih.gov/pubmed/18202134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1422
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