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Identification of Cyclic Adenosine 3′,5′-Monophosphate Response Element Modulator as an Activator of the Human Sodium/Iodide Symporter Upstream Enhancer
The lack of Na(+)/I(−) symporter (NIS) gene expression in some thyroid cancer patients has been a major hurdle that limits the efficacy of standard radioactive iodide therapy. The molecular mechanism that contributes to low NIS expression is not well understood. Activated NIS gene expression is stim...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Endocrine Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2329265/ https://ncbi.nlm.nih.gov/pubmed/18202121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1390 |
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