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Gonadotropin-Releasing Hormone (GnRH) Activates the M-Current in GnRH Neurons: An Autoregulatory Negative Feedback Mechanism?

GnRH autoregulates GnRH neurons through an ultrashort feedback loop. One potential mechanism is the regulation of K(+) channel activity through the GnRH receptor. Whereas GnRH inhibits the activity of the M-current in peripheral neurons, there is no direct evidence that the M-current is involved in...

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Autori principali: Xu, Chun, Roepke, Troy A., Zhang, Chunguang, Rønnekleiv, Oline K., Kelly, Martin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329261/
https://ncbi.nlm.nih.gov/pubmed/18218690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1178
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