Evidence for rapid disappearance of initially expanded HIV-specific CD8(+) T cell clones during primary HIV infection

Down-regulation of the initial burst of viremia during primary HIV infection is thought to be mediated predominantly by HIV-specific cytotoxic T lymphocytes, and the appearance of this response is associated with major perturbations of the T cell receptor repertoire. Changes in the T cell receptor r...

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Detalhes bibliográficos
Main Authors: Pantaleo, Giuseppe, Soudeyns, Hugo, Demarest, James F., Vaccarezza, Mauro, Graziosi, Cecilia, Paolucci, Stefania, Daucher, MaryBeth, Cohen, Oren J., Denis, François, Biddison, William E., Sekaly, Rafick P., Fauci, Anthony S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23280/
https://ncbi.nlm.nih.gov/pubmed/9275214
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