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Correspondences between low-energy modes in enzymes: Dynamics-based alignment of enzymatic functional families
Proteins that show similarity in their equilibrium dynamics can be aligned by identifying regions that undergo similar concerted movements. These movements are computed from protein native structures using coarse-grained elastic network models. We show the existence of common large-scale movements i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2327282/ https://ncbi.nlm.nih.gov/pubmed/18369194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073390208 |
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