Gα(i2) inhibition of adenylate cyclase regulates presynaptic activity and unmasks cGMP-dependent long-term depression at Schaffer collateral-CA1 hippocampal synapses

Cyclic AMP signaling plays a central role in regulating activity at a number of synapses in the brain. We showed previously that pairing activation of receptors that inhibit adenylate cyclase (AC) and reduce the concentration of cyclic AMP, with elevation of the concentration of cyclic GMP is suffic...

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Bibliografische gegevens
Hoofdauteurs: Bailey, Christopher P., Nicholls, Russell E., Zhang, Xiao-lei, Zhou, Zhen-yu, Müller, Wolfgang, Kandel, Eric R., Stanton, Patric K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2008
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327268/
https://ncbi.nlm.nih.gov/pubmed/18391187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.810208
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