Up-regulation of β-chemokines and down-modulation of CCR5 co-receptors inhibit simian immunodeficiency virus transmission in non-human primates

A non-cognate mechanism of protection against human immunodeficiency virus-1 (HIV-1) infection involves up-regulation of β-chemokines, which bind and may down-modulate the CCR5 co-receptors, thereby preventing transmission of M-tropic HIV-1. The objective of this investigation was to evaluate this m...

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Bibliographische Detailangaben
Hauptverfasser: Lehner, T, Wang, Y, Cranage, M, Tao, L, Mitchell, E, Bravery, C, Doyle, C, Pratt, K, Hall, G, Dennis, M, Villinger, L, Bergmeier, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2000
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327186/
https://ncbi.nlm.nih.gov/pubmed/10792505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00993.x
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