CXC chemokine receptor 4 expression and stromal cell-derived factor-1α-induced chemotaxis in CD4(+) T lymphocytes are regulated by interleukin-4 and interleukin-10

We report that interleukin (IL)-4 and IL-10 can significantly up- or down-regulate CXC chemokine receptor 4 (CXCR4) expression on CD4(+) T lymphocytes, respectively. Stromal cell-derived factor-1α (SDF-1α)-induced CD4(+) T-lymphocyte chemotaxis was also correspondingly regulated by IL-4 and IL-10. I...

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Autores principales: Jinquan, T, Quan, S, Jacobi, H H, Madsen, H O, Glue, C, Skov, P S, Malling, H-J, Poulsen, L K
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2000
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327181/
https://ncbi.nlm.nih.gov/pubmed/10712670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00954.x
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