Inhibition of contact sensitivity in human CD4(+) transgenic mice by human CD4-specific monoclonal antibodies: CD4(+) T-cell depletion is not required

Clenoliximab and keliximab are monkey/human chimeric monoclonal antibodies (mAbs) of the immunoglobulin G4 (IgG4) and IgG1 isotypes, respectively, that recognize the same epitope on human CD4. The two mAbs possess identical idiotypes and exhibit equal affinities for CD4. Upon administration of these...

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Detalhes bibliográficos
Main Authors: Podolin, P L, Webb, E F, Reddy, M, Truneh, A, Griswold, D E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327156/
https://ncbi.nlm.nih.gov/pubmed/10692049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00946.x
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