In vivo rapid reduction of alloantigen-activated CD8(+) mature cytotoxic T cells by inhibitors of acidification of intracellular organelles, prodigiosin 25-C and concanamycin B

Prodigiosin (PrG) 25-C and concanamycin B (CMB) are immunosuppressants that specifically inhibit the induction of cytotoxic T cells (CTL) without affecting the function of B cells and helper T cells in vivo. Both compounds inhibit acidification of intracellular organelles and induce destruction of c...

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Main Authors: Lee, M-H, Kataoka, T, Honjo, N, Magae, J, Nagai, K
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2000
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327146/
https://ncbi.nlm.nih.gov/pubmed/10692043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00961.x
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