Inhibition of immunoglobulin E response to Japanese cedar pollen allergen (Cry j 1) in mice by DNA immunization: different outcomes dependent on the plasmid DNA inoculation method

To develop a new immunotherapy for Japanese cedar (Cryptomeria japonica; CJ) pollinosis, we evaluated the use of DNA immunization by inoculating mice with plasmid DNA encoding Cry j 1 as a CJ pollen major allergen (pCACJ1). Repeated intramuscular (i.m.) inoculation of BALB/c mice with pCACJ1 produce...

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Detalhes bibliográficos
Main Authors: Toda, M, Sato, H, Takebe, Y, Taniguchi, Y, Saito, S, Inouye, S, Takemori, T, Sakaguchi, M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327145/
https://ncbi.nlm.nih.gov/pubmed/10692034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00935.x
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