CpG-oligodeoxynucleotides enhance T-cell receptor-triggered interferon-γ production and up-regulation of CD69 via induction of antigen-presenting cell-derived interferon type I and interleukin-12

Bacterial cytidine–phosphate–guanosine (CpG-DNA) activates antigen-presenting cells (APC) and drives T helper 1 (Th1)-polarized immune responses in the mouse. Claims have been made that CpG-DNA costimulates murine T cells. We examined the direct and indirect effects of CpG-oligodeoxynucleotides (CpG...

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Main Authors: Kranzer, K, Bauer, M, Lipford, G B, Heeg, K, Wagner, H, Lang, R
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2000
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327140/
https://ncbi.nlm.nih.gov/pubmed/10692033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00964.x
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