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Immunity to vaginal herpes simplex virus-2 infection in B-cell knockout mice

We investigated the involvement of antibody in protection against vaginal herpes simplex virus type-2 (HSV-2) infection by comparing intact and B-cell knockout (KO) mice. Vaginal immunization of intact mice with attenuated HSV-2 markedly reduced an HSV-2 challenge infection in the vagina. In contras...

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Autori principali: Parr, M B, Parr, E L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327048/
https://ncbi.nlm.nih.gov/pubmed/11012763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00080.x
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