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Failure to remove autoreactive Vβ6(+) T cells in Mls-1(a) newborn mice attributed to the delayed development of B cells in the thymus
Clonal deletion of autoreactive T cells in the thymus is one of the major mechanisms for establishing tolerance to self-antigens, and self-reactive T cells bearing Vβ6 T-cell receptors are usually deleted before their maturation in Mls-1(a) mice. However, these T cells develop transiently in the neo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2000
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2327038/ https://ncbi.nlm.nih.gov/pubmed/10929068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00058.x |
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