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Tetanus toxin L chain is processed by major histocompatibility complex class I and class II pathways and recognized by CD8(+) or CD4(+) T lymphocytes
Tetanus toxin (TeNT) is a heterodimeric protein antigen, whose light chain (L) is translocated in the cytosol of neuronal target cells specifically to cleave its substrates, vesicle-associated membrane protein-2 (VAMP-2, or synaptobrevin) or cellubrevin. We report that the L chain behaves as a nomin...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2327006/ https://ncbi.nlm.nih.gov/pubmed/10886393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00032.x |
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