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Antibody repertoire development in fetal and newborn piglets, III. Colonization of the gastrointestinal tract selectively diversifies the preimmune repertoire in mucosal lymphoid tissues

Changes in the V(H)-region repertoire of isolator piglets reared for 6 weeks under germ-free (GF) conditions and those colonized (COL) with a defined exclusion flora on the 1st day of life were compared. Although serum immunoglobulin levels were 20–100-fold higher in COL piglets than GF piglets, an...

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Bibliografiska uppgifter
Huvudupphovsmän: Butler, J E, Sun, J, Weber, P, Navarro, P, Francis, D
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326983/
https://ncbi.nlm.nih.gov/pubmed/10809967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00013.x
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