Deficiency of the macrophage migration inhibitory factor gene has no significant effect on endotoxaemia

By targeted disruption of the MIF gene, we have established a mouse strain deficient in macrophage (Mφ) migration inhibitory factor (MIF). Despite previous reports indicating an essential role of MIF in endotoxaemia, an injection of lipopolysaccharide (LPS) into the MIF-deficient mice (maintained un...

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Autors principals: Honma, N, Koseki, H, Akasaka, T, Nakayama, T, Taniguchi, M, Serizawa, I, Akahori, H, Osawa, M, Mikayama, T
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2000
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326981/
https://ncbi.nlm.nih.gov/pubmed/10809963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2000.00011.x
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