Lack of activation induced cell death in human T blasts despite CD95L up‐regulation: protection from apoptosis by MEK signalling

The generation of effective immunity requires that antigen‐specific T cells are activated, clonally expanded and ultimately eliminated by apoptosis. The involvement of CD95‐mediated apoptosis in T‐cell elimination is well established, but the conditions which regulate the death pathway under normal...

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Autori principali: Walker, L S K, Mcleod, J D, Boulougouris, G, Patel, Y I, Ellwood, C N, Hall, N D, Sansom, D M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1999
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326970/
https://ncbi.nlm.nih.gov/pubmed/10594690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00925.x
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