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Selective correlation of interferon-γ, tumour necrosis factor-α and granulocyte–macrophage colony-stimulating factor with immunoglobulin G1 and immunoglobulin G3 subclass antibody in leprosy

Dysregulation of both B- and T-cell responses is observed in leprosy. Immunoglobulin G1 (IgG1) and IgG3 antibody subclasses are selectively elevated towards the lepromatous or disseminated form of the disease accompanied by a depression of T-cell responses. T-cell and macrophage cytokines influence...

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Autores principales: Hussain, R, Kifayet, A, Dojki, M, Dockrell, H M
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326927/
https://ncbi.nlm.nih.gov/pubmed/10540222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00876.x
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