FcγRI activation of phospholipase Cγ1 and protein kinase C in dibutyryl cAMP-differentiated U937 cells is dependent solely on the tyrosine-kinase activated form of phosphatidylinositol-3-kinase

The human high affinity receptor for immunoglobulin G, FcγRI, in dibutyryl cyclic AMP (dbcAMP)-differentiated U937 cells, is coupled to the activation of phospholipase C (PLC) and the conventional protein kinase C (PKC) isoforms, α, β, and γ. Here we demonstrate that aggregation of FcγRI activates t...

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Bibliografiska uppgifter
Huvudupphovsmän: Melendez, A J, Harnett, M M, Allen, J M
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Science Inc 1999
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326909/
https://ncbi.nlm.nih.gov/pubmed/10469227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00833.x
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