Regulation of major histocompatibility complex class II antigens on human alveolar macrophages by granulocyte–macrophage colony-stimulating factor in the presence of glucocorticoids

Alveolar macrophages (AM) present antigen poorly to CD4(+) T cells and respond weakly to interferon-γ (IFN-γ) for up-regulation of major histocompatibility complex (MHC) class II and costimulatory molecule expression. In atopic asthma, however, AM exhibit enhanced antigen-presenting cell (APC) activ...

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Main Authors: Caulfield, J J, Fernandez, M H, Sousa, A R, Lane, S J, Lee, T H, Hawrylowicz, C M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326900/
https://ncbi.nlm.nih.gov/pubmed/10469240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00862.x
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