Depletion of CD8(+) cells abolishes memory in acquired immunity against Chlamydia pneumoniae in BALB/c mice

The importance of T cells in Chlamydia pneumoniae infection in mice was assessed by comparing wild-type BALB/c mice with nude mice and mice depleted in vivo of either CD4(+) or CD8(+) T cells. Whereas wild-type mice cleared the primary infection in 3 weeks, nude mice were only able to restrict the i...

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Detalhes bibliográficos
Main Authors: Penttilä, J M, Anttila, M, Varkila, K, Puolakkainen, M, Sarvas, M, Mäkelä, P H, Rautonen, N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326855/
https://ncbi.nlm.nih.gov/pubmed/10447772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00809.x
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