Intravenous tolerization with type II collagen induces interleukin-4-and interleukin-10-producing CD4(+) T cells

Intravenous (i.v.) administration of type II collagen (CII) is an effective way to induce tolerance and suppress disease in the collagen-induced arthritis (CIA) model. In this study, we demonstrated that a single i.v. dose of CII (as low as 0·1 mg/mouse) completely prevented the development of CIA....

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Detalhes bibliográficos
Main Authors: Gumanovskaya, M L, Myers, L K, Rosloniec, E F, Stuart, J M, Kang, A H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326845/
https://ncbi.nlm.nih.gov/pubmed/10447769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00778.x
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