The production of interleukin-1β from human fetal membranes is not obligatory for increased prostaglandin output

Bacterial endotoxin increased the expression of mRNA (maximal after 4 hr) for interleukin-1β (IL-1β) and the release of mature protein from intact human fetal membranes. In contrast, the change in expression of mRNA for type 2 cyclo-oxygenase (COX-2) was biphasic, with peaks after 0·5–1 hr and after...

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Hauptverfasser: Alvi, S A, Rajasingam, D, Brown, N L, Elder, M G, Bennett, P R, Sullivan, M H F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 1999
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326835/
https://ncbi.nlm.nih.gov/pubmed/10447739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00769.x
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