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Induction of the trypanosome lymphocyte-triggering factor (TLTF) and neutralizing antibodies to the TLTF in experimental African trypanosomiasis
We have demonstrated that African trypanosomes secrete a novel trypanokine, the trypanosome-derived lymphocyte-triggering factor (TLTF), which activates CD8(+) cells to produce interferon-γ (IFN-γ) that in turn stimulates parasite growth. The gene for TLTF was recently cloned, and recombinant TLTF (...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Science Inc
1999
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2326788/ https://ncbi.nlm.nih.gov/pubmed/10233748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00730.x |
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