Co-immunization with DNA vaccines expressing granulocyte–macrophage colony-stimulating factor and mycobacterial secreted proteins enhances T-cell immunity, but not protective efficacy against Mycobacterium tuberculosis

The development of more effective antituberculosis vaccines would assist in the control of the global problem of infection with Mycobacterium tuberculosis. One recent vaccination strategy is immunization with DNA plasmids encoding individual microbial genes. Using the genes for the M. tuberculosis-s...

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Bibliographic Details
Main Authors: Kamath, A T, Hanke, T, Briscoe, H, Britton, W J
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 1999
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326784/
https://ncbi.nlm.nih.gov/pubmed/10233735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00703.x
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