Direct evidence that ERK regulates the production/secretion of interleukin-2 in PHA/PMA-stimulated T lymphocytes

Although p21(ras), raf-1 and MEK have been shown to regulate directly the transcriptional activity of NFAT (nuclear factor of activated T cells) and/or the interleukin-2 (IL-2) promoter, direct evidence that the extracellular signal-regulated protein kinase (ERK) is involved in regulating IL-2 produ...

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Autors principals: Li, Y Q, Hii, C S T, Der, C J, Ferrante, A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1999
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326783/
https://ncbi.nlm.nih.gov/pubmed/10233737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00724.x
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