The polymorphisms S503P and Q576R in the interleukin-4 receptor α gene are associated with atopy and influence the signal transduction

Interleukin-4 (IL-4) plays a major role in immunoglobulin E (IgE) production. Its signal is conferred to effector cells through binding to the α chain of the IL-4 receptor (IL-4Rα). We present further evidence for polymorphisms in the IL-4Rα gene having an effect on IgE regulation. For two of four c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kruse, S, Japha, T, Tedner, M, Sparholt, SH, Forster, J, Kuehr, J, Deichmann, KA
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 1999
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326760/
https://ncbi.nlm.nih.gov/pubmed/10233717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00705.x
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