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Extrathymic derivation of gut lymphocytes in parabiotic mice

In adult mice, c-kit(+) stem cells have recently been found in their liver, intestine and appendix, where extrathymic T cells are generated. A major population of such thymus-independent subsets among intraepithelial lymphocytes is T-cell receptor (TCR)γδ(+) CD4(−) CD8αα(+)(β(−)) cells, but the orig...

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Detalhes bibliográficos
Main Authors: Sugahara, S, Shimizu, T, Yoshida, Y, Aiba, T, Yamagiwa, S, Asakura, H, Abo, T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326721/
https://ncbi.nlm.nih.gov/pubmed/10233678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00665.x
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