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The protein product of the het-s heterokaryon incompatibility gene of the fungus Podospora anserina behaves as a prion analog

The het-s locus of Podospora anserina is a heterokaryon incompatibility locus. The coexpression of the antagonistic het-s and het-S alleles triggers a lethal reaction that prevents the formation of viable heterokaryons. Strains that contain the het-s allele can display two different phenotypes, [Het...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Coustou, Virginie, Deleu, Carol, Saupe, Sven, Begueret, Joel
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23266/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9275200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.18.9773
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