Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage.

We have cloned the human mutY gene (hMYH) from both genomic and cDNA libraries. The human gene contains 15 introns and is 7.1 kb long. The 16 exons encode a protein of 535 amino acids that displays 41% identity to the Escherichia coli protein, which provides an important function in the repair of ox...

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Detalles Bibliográficos

Publicado en:	J Bacteriol
Autores principales:	Slupska, M M, Baikalov, C, Luther, W M, Chiang, J H, Wei, Y F, Miller, J H
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232650/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8682794/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.13.3885-3892.1996
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