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Differential recognition of liganded and unliganded thyroid hormone receptor by retinoid X receptor regulates transcriptional repression.

Thyroid hormone receptor (TR) functions as part of multiprotein complexes that also include retinoid X receptor (RXR) and transcriptional coregulators. We have found that both the TR CoR box and ninth heptad are required for RXR interaction and in turn for interaction with corepressor proteins N-CoR...

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Publicat a:Mol Cell Biol
Autors principals: Zhang, J, Zamir, I, Lazar, M A
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232545/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9372920/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.12.6887
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