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Synergistic activation of NF-kappaB by tumor necrosis factor alpha and gamma interferon via enhanced I kappaB alpha degradation and de novo I kappaBbeta degradation.

Tumor necrosis factor alpha (TNF-alpha) and gamma interferon (IFN-gamma) are required for an effective immune response to bacterial infection and these cytokines synergize in a variety of biological responses, including the induction of cytokine, cell adhesion, and inducible nitrous oxide synthase g...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Cheshire, J L, Baldwin, A S
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232529/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.11.6746
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