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Specific DNA binding of Stat5, but not of glucocorticoid receptor, is required for their functional cooperation in the regulation of gene transcription.

Prolactin and glucocorticoid hormone are signals which regulate the transcription of milk protein genes in mammary epithelial cells. We have investigated the molecular mechanisms by which these hormones cooperate in the induction of transcription. Both hormones activate latent transcription factors...

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Publicat a:Mol Cell Biol
Autors principals: Stoecklin, E, Wissler, M, Moriggl, R, Groner, B
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1997
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232525/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343435/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.11.6708
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