The intermembrane space domain of mitochondrial Tom22 functions as a trans binding site for preproteins with N-terminal targeting sequences.
Mitochondrial protein import is thought to involve the sequential interaction of preproteins with binding sites on cis and trans sides of the membranes. For translocation across the outer membrane, preproteins first interact with the cytosolic domains of import receptors (cis) and then are transloca...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1997
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232511/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9343421/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.11.6574 |
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