VP16 targets an amino-terminal domain of HCF involved in cell cycle progression.

The herpes simplex virus (HSV) regulatory protein VP16 activates HSV immediate-early gene transcription through formation of a multiprotein-DNA complex on viral promoters that includes the preexisting nuclear proteins HCF and Oct-1. The HCF protein is a complex of amino- and carboxy-terminal polypep...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Wilson, A C, Freiman, R N, Goto, H, Nishimoto, T, Herr, W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232464/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9315674/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.10.6139
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