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Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells

BACKGROUND: Statins are shown to have cholesterol-independent properties such as anti-inflammation and immunomodulation. Activated hepatic stellate cells (HSCs) acquire the capacity to synthesize matrix proteins in damaged liver. We tested the hypothesis that atorvastatin may be capable of inducing...

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Detalhes bibliográficos
Main Authors: Aprigliano, Isabella, Dudas, Joszef, Ramadori, Giuliano, Saile, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2324535/
https://ncbi.nlm.nih.gov/pubmed/18339080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2008.01682.x
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